基本信息
姓名：郭信东
职称：讲师
专业：中药学
研究方向：中药药效物质基础
开设课程：新药的开发与上市
电邮：guoxindong007@163.com
个人简介
郭信东，男，博士，讲师，2020年7月毕业于黑龙江中医药大学中药化学专业，主要从事中药药效物质基础，中药质谱分析，中药质量评价等方面的研究。近三年主要从事中药三萜皂苷质谱分析方法的建立及应用研究。2022年获贵州中医药大学“我最喜爱的教师”荣誉称号，同年，指导本科生获得省级大学生创新创业训练计划1项。
科研项目
贵中医博士启动[2021]01号；2023年贵州中医药大学学术新苗项目等。
科研成果或科技服务
夏永刚; 梁军; 郭信东; 宋艳 ; 基于电喷雾质子化裂解定量中药三萜皂苷含量所需碰撞能的预测方法,2021-5-11, 中国,ZL20181085 0022.5。
发表的论文及著作
[1] 郭信东,杨昌贵,肖承鸿,周涛. HILIC-UPLC-MS/MS法鉴定知母中皂苷类成分[J].中华中医药杂志,2021,36(12):7292-7301.
[2] 郭信东,袁小凤,杨昌贵,肖承鸿.黄精酒制后活性成分的变化研究[J].时珍国医国药,2021,32(325):73-75.
[3] 沈良洪; 翟欣欣; 李鹏飞; 郭信东*.响应面法优化黄精活性成分的提取工艺, 化学工程师, 2023,11: 108-113.
[4] Yong-Gang Xia∗, Xin-Dong Guo, Yan Song, Jun Liang, Feng-Qiu Gong, Tian-Long Wang, Bing-You Yang, Hai-Xue Kuang∗，A generic strategy based on gas phase decomposition of protonated and ammoninted precursors producing predictable MRM-MS ion pairs and collision energies for direct analysis of plant triterpene glycosides, Journal of Pharmaceutical and Biomedical Analysis, 2019,165,292–303.
[5] 郭信东,梁军,宫凤秋,夏永刚,匡海学.知母呋甾烷醇型皂苷的质谱裂解行为研究[J].中医药学报,2016,05:11-14.
[6] Yong-Gang Xia, Xin-Dong Guo, Jun Liang, Bing-You Yang, Hai-Xue Kuang, Screening and identification of steroidal saponins from Anemarrhena asphodeloides employing UPLC tandem triple quadrupole linear ion trap mass spectrometry, Steroids, 2017, 25, 67-80.
[7] Yong‐Gang Xia1, Jun Liang1, Xin‐Dong Guo, Hui‐Min Sun, Hai‐Xue Kuang, UPLC‐ QTOF‐MSE‐based diagnostic product ion filtering to unveil unstable C6‐C2glucoside conjugates in Forsythia suspensa, Journal of Mass Spectrometry, 2017, 52, 848-859.
[8] Jun Liang, Xin-Dong Guo and Fang Han, UHPLC-ESI-MS/MS quantitative analyzes of multicomponent Hu-Gan Tablets, Molecules, 2019, 24, 4241.
[9] Yong-Gang Xia∗, Feng-Qiu Gong, Xin-Dong Guo, Yan Song, Chen-Xue Li, Jun Liang, Bing-You Yang, Hai-Xue Kuang∗, Rapid screening and characterization of triterpene saponins in Acanthopanax senticosus leaves via untargeted MS All and SWATH techniques on a quadrupole time of flight mass spectrometry, Journal of Pharmaceutical and Biomedical Analysis, 2019,170,68–82.
[10] Yong-Gang Xia, Yan Song, Jun Liang, Xin-Dong Guo, Bing-You Yang and Hai-Xue Kuang, Quality Analysis of American Ginseng Cultivated in Heilongjiang Using UPLC-ESI-MRM-MS with Chemometric Methods, Molecules, 2018, 23, 2396.
[11] 梁军，郭信东，夏永刚，杨炳友，王秋红，匡海学. UPLC同时测定不同产地连翘中8种成分[J].中国实验方剂学杂志,2017,23,11:68-72.
[12] 夏永刚，宫凤秋，郭信东，宋艳，梁军，匡海学. 3个辽东楤木三萜皂苷同分异构体的电喷雾质谱区分[J],中国实验方剂学杂志, 2018,24, 42-48.
[13]夏永刚，宫凤秋，郭信东，梁军，匡海学,知母、麦冬和薯蓣中螺甾体皂苷的质谱裂解规律研究[J],中医药学报, 2017, 45,10-13.
[14]梁军,夏永刚,郭信东,王天龙,匡海学.超高效液相色谱-高分辨质谱法同时测定类叶牡丹中9种三萜皂苷类成分[J].中草药,2017,48(20):4323-4327.
[15]孙黎明,梁军,王杰姝,郭信东,夏永刚,匡海学.护肝片中5种木脂素成分的高效液相-荧光检测研究[J].中医药学报,2015,43(03):13-16.
